ORA-15564: contents of the replay directory provided to the workload replay client do not match with the replay directory provided to the database server

This can happen due to many different reasons.Some of the reasons I have noticed while running a DB replay were.

1)During connection remapping you are not providing the same connection string/service name as to the replay client.
2) The replay directory is not accessible from all the instances.
3) Replay workload is not pre-processed or it is pre-processed on some other version of the database as the target database.